Fc-receptor function after human splenic autotransplantation.

Fc-receptor Function after Human Splenic Autotransplantation

ارزیابی تغییرات سلولی بافت طحال و تغییرات سرولوژیک خون محیطی در اتوترانسپلنتیشن طحال در مقایسه با موارد اسپلنکتومی شده در رت

 Background & Aims: Spleen is one of the most common sites of injury after trauma. When splenectomy due to spleen damage is unavoidable, autotransplantation of splenic tissue is the only possible option to preserve splenic function. Immunologic function of spleen against infections is unremarkable but compensation levels of immunological activity and structural rearrangement of transplanted spl...

The value of partial splenic autotransplantation in patients with portal hypertension: a prospective randomized study.

HYPOTHESIS Splenic autotransplantation plays a role in preserving immune function of the spleen in patients with portal hypertension and liver cirrhosis. DESIGN Prospective randomized study. SETTING University hospital. PATIENTS Twenty patients (19 men and 1 woman; aged 33-80 years) suffering from portal hypertension and liver cirrhosis were randomly allocated into 2 groups. Each group co...

Splenic autotransplantation in a patient with human immunodeficiency virus infection: a case report

INTRODUCTION Splenectomy is performed mostly because of traumatic events that cause rupture of the spleen. Postsplenectomy, a patient has a higher risk of developing sepsis. Autotransplantation of splenic tissue decreases the risk of opportunistic infection and sepsis, but its role in patients with human immunodeficiency virus is debated because the spleen is a replication site, especially duri...

Immune response capacity after human splenic autotransplantation: restoration of response to individual pneumococcal vaccine subtypes.

OBJECTIVE To evaluate features of general immune function, in particular the restoration of the humoral immune response to pneumococcal capsular polysaccharides, in humans undergoing a spleen autotransplantation after splenectomy because of trauma. SUMMARY BACKGROUND DATA After splenectomy, patients have an increased risk of overwhelming infection or sepsis involving encapsulated bacteria suc...